Title
Auditory neuropathy : a challenge for diagnosis and treatment
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Brussel ,
Subject
Human medicine
Source (journal)
Acta oto-rhino-laryngologica Belgica. - Brussel
Volume/pages
9(2013) :S:21 , p. 65-79
ISSN
0001-6497
ISI
000327831800010
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
In current terminology, auditory neuropathy spectrum disorder (ANSD) is a disease involving the disruption of the temporal coding of acoustic signals in auditory nerve fibres, resulting in the impairment of auditory perceptions that rely on temporal cues. There is debate about almost every aspect of the disorder, including aetiology, lesion sites, and the terminology used to describe it. ANSD is a heterogeneous disease despite similar audiological findings. The absence of an auditory brainstem response (ABR) and the presence of otoacoustic emissions (OAE) suggest an ANSD profile. However, to determine the exact anatomical site of the disorder, more in-depth audiological and electrophysiological tests must be combined with imaging, genetics and neurological examinations. Greater diagnostic specificity is therefore needed to provide these patients with more adequate treatment.
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