Title
Synthesis of 4-aminoquinolines by aerobic oxidative palladium-catalyzed double CH activation and isocyanide insertion Synthesis of 4-aminoquinolines by aerobic oxidative palladium-catalyzed double CH activation and isocyanide insertion
Author
Faculty/Department
Faculty of Sciences. Chemistry
Publication type
article
Publication
New York ,
Subject
Chemistry
Source (journal)
Chemistry of heterocyclic compounds. - New York
Volume/pages
49(2013) :6 , p. 902-908
ISSN
0009-3122
ISI
000324215000010
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
An unprecedented aerobic oxidative Pd-catalyzed imidoylative coupling of two CH fragments furnishing medicinally valuable 4-aminoquinolines is reported. Optimization studies are described and several analogs were successfully prepared.
E-info
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