Publication
Title
Isolation of high-quality RNA from stented blood vessels
Author
Abstract
Stents have become a standard of care for the treatment of coronary artery disease. A series of cellular and molecular processes contribute to the vascular response following stent placement. For the purpose of local gene expression studies, metallic stent struts are usually removed from the vessel wall with forceps under a dissection microscope prior to RNA extraction. Main drawbacks of the manual dissection are that it may cause additional tissue damage and compromise the quality of RNA through prolonged tissue handling. In this technical note, we report the recovery of high-quality RNA from atherosclerotic vessels with stent struts left in situ.
Language
English
Source (journal)
Microvascular research. - New York, N.Y.
Publication
New York, N.Y. : 2013
ISSN
0026-2862
Volume/pages
89(2013), p. 161-163
ISI
000324011900021
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 17.02.2014
Last edited 04.07.2017
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