Publication
Title
Mechanisms of soft cellular tissue bruising : a particle based simulation approach
Author
Abstract
This paper is concerned with modeling the mechanical behavior of cellular tissue in response to dynamic stimuli. The objective is to investigate the formation of bruises and other damage in tissue under excessive loading. We propose a particle based model to numerically study cells and aggregates of cells described on to subcellular detail. The model focuses on a parenchyma cell type in which two important features are present: the cell's interior liquid-like phase inducing hydrodynamic phenomena; and the cell wall, a viscoelastic-plastic solid membrane that encloses the protoplast. The cell fluid is modeled by a Smoothed Particle Hydrodynamics (SPH) technique, while for the cell wall and cell adhesion a nonlinear discrete element model is proposed. Failure in the system is addressed to either cell wall rupture or to debonding of the middle lamella. We show that the model is able to reproduce experimental data of quasistatic compression, and investigate the role of the protoplasm viscosity and the cellular structure on the dynamics of the aggregate system. This indicates that a high viscosity causes better guidance of mechanical stresses through the tissue and can result in a higher penetration of damage, whereas low values will cause more local bruising effects.
Language
English
Source (journal)
Soft matter. - Cambridge
Publication
Cambridge : 2011
ISSN
1744-683X
Volume/pages
7:7(2011), p. 3580-3591
ISI
000288677200067
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 24.02.2014
Last edited 17.07.2017