Title
Targeting the ErbB family in head and neck cancer Targeting the ErbB family in head and neck cancer
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Subject
Human medicine
Source (journal)
European oncological disease
Volume/pages
2(2007) , p. 35-40
ISSN
1753-4100
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
Head and neck cancer is the sixth most common cancer, representing about 5% of all cancers. Each year, more than half a million new cases are diagnosed worldwide.13 Over the past decade, the important role of different growth factors and their receptors and signal transduction pathways in the genesis and progression of tumours has been well recognised, and their mechanism of action and interaction is gradually being unravelled.410 The ErbB family comprises four members: human epidermal growth factor receptor (EFGR; HER 1), HER2 (c-erb-B2), HER3 (cerb- B3) and HER4 (c-erb-B4).
E-info
https://repository.uantwerpen.be/docman/iruaauth/b1f829/12762c8b8f1.pdf
Handle