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Title
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Sample evaporation from pierceable cups : still an important source of analytical error
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Author
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Abstract
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| Background We illustrate the impact of sample evaporation on analytical results in laboratory practice and highlight preventive measures. Methods Plasma (n = 10) was analysed for glucose, Na+, HCO3− and calcium on six different sample configurations at 5 time points within 2 h. Results With time glucose, Na+ and calcium values increased and HCO3− values decreased in a clinically significant way. Conclusions Analytical error due to evaporation may be significant, but can be reduced with optimal sample handling. A pierceable cover does not prevent loss of HCO3−. |
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Language
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English
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Source (journal)
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Clinical biochemistry. - Toronto, Ont.
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Publication
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Toronto, Ont.
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2010
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ISSN
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0009-9120
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DOI
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10.1016/J.CLINBIOCHEM.2010.09.004
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Volume/pages
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43
:18
(2010)
, p. 1464-1467
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ISI
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000284520200018
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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