Title
Intrathecal chloroprocaine vs. lidocaine in day-case surgery : recovery, discharge and effect of pre-hydration on micturition Intrathecal chloroprocaine vs. lidocaine in day-case surgery : recovery, discharge and effect of pre-hydration on micturition
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Copenhagen ,
Subject
Human medicine
Source (journal)
Acta anaesthesiologica scandinavica. - Copenhagen
Volume/pages
58(2014) :2 , p. 206-213
ISSN
0001-5172
ISI
000330633200010
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
BackgroundThis randomised, double blind prospective study compares intrathecal lidocaine with chloroprocaine in day-case surgery and the influence of a 500ml pre-load intravenously. We tested the hypothesis that chloroprocaine provides faster recovery and discharge in day-case surgery. Secondary we studied the influence of a preload compared with fluid restriction on discharge time and micturition problems. MethodsOne hundred patients undergoing day-case arthroscopy were randomised to receive either lidocaine (L) 60mg or chloroprocaine (CP) 40mg intrathecally and this with (L+, CP+) or without (L-, CP-) a 500ml pre-load of crystalloid. Block characteristics, micturition and discharge times were registered. Bladder volumes were monitored by ultrasound. Micturition problems received a micturition score. ResultsOnset and quality of the block were comparable between groups. Time to regain Bromage 1 and L2 regression were shorter for the CP group compared with the L group. Voiding (16844min) and discharge (178 +/- 52min) were approximately 40min faster for the CP group compared with the L group. Pre-load provided faster bladder filling but there were no differences in voiding time within the CP or L group. The CP+ group (166 +/- 36min) was discharged faster than both L groups (226 +/- 57min, 227 +/- 59min). More serious micturition problems occurred in the L+ group compared with both CP groups. ConclusionChloroprocaine is suitable for day-case surgery because of faster block regression and discharge than lidocaine. A 500ml pre-load may not affect discharge but did not increase micturition problems for chloroprocaine. (C) 2013 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd
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