Publication
Title
Normative values for corneal densitometry analysis by Scheimpflug optical assessment
Author
Abstract
PURPOSE. To describe the normative data for corneal Scheimpflug densitometry based on a cohort of normal participants. METHODS. A total of 445 healthy participants were recruited for assessment (794 eyes). Left and right eyes were considered separately. All participants were assessed using the corneal densitometry analysis add-on to the standard software of the Oculus Pentacam. Densitometry measurements were obtained and expressed in standardized grayscale units (GSU). RESULTS. All participants were Caucasian; 42% were male and 58% were female. The mean age was 48.0 +/- 15.3 years (range, 20.2-84.2 years). Mean corneal densitometry over the 12-mm-diameter area was 19.74 +/- 3.89 GSU. When divided by radial zone, densitometry values were lowest in the central zone (16.76 +/- 1.87 GSU) and highest in the periphery (27.36 +/- 7.47 GSU). There was no difference between central zone and the surrounding 2- to 6-mm annulus (P > 0.05), though the 6- to 10-mm and the 10- to 12-mm zones displayed higher densitometry values (P < 0.001). When divided by depth, the anterior layer displayed the highest densitometry reading of 25.81 +/- 5.14 GSU, which was significantly higher than that of both the central (P < 0.001) and the posterior layers (P < 0.001). Changes in corneal densitometry were correlated with age, though not within the central 6-mm-diameter ring. No sex difference was seen within the cohort. CONCLUSIONS. This add-on to the standard imaging software allows rapid and objective assessment of the corneal densitometry. We provide normative data that may be used as a reference facilitating research and complementing clinical examination.
Language
English
Source (journal)
Investigative ophthalmology and visual science. - St. Louis, Mo.
Publication
St. Louis, Mo. : 2014
ISSN
0146-0404
Volume/pages
55:1(2014), p. 162-168
ISI
000331877200018
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 04.04.2014
Last edited 07.08.2017
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