Complete genome sequences of nitrofurantoin-sensitive and -resistant **Escherichia coli** ST540 and ST2747 strainsComplete genome sequences of nitrofurantoin-sensitive and -resistant **Escherichia coli** ST540 and ST2747 strains
Faculty of Medicine and Health Sciences
Vaccine & Infectious Disease Institute (VAXINFECTIO)
2014Washington, D.C., 2014
Genome announcements. - Washington, D.C.
2(2014):2, p. 1-2
University of Antwerp
Widespread multidrug resistance in Escherichia coli has necessitated the reintroduction of older antibiotics, such as nitrofurantoin. However, mechanisms by which resistance to nitrofurantoin emerges in E. coli are not well elucidated. Toward this aim, we sequenced two nitrofurantoin-sensitive E. coli sequence types (ST540 and ST2747) and their four nitrofurantoin-resistant derivatives generated in vitro under aerobic and anaerobic growth conditions.