Matrix effects and analysis of biological material by spark source mass spectrometryMatrix effects and analysis of biological material by spark source mass spectrometry
Faculty of Sciences. Chemistry
AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Fresenius' Zeitschrift für analytische Chemie. - München, 1947 - 1989
321(1985):1, p. 32-36
University of Antwerp
Spark-source mass spectrometric analyses of synthetic simulated biological samples were performed to determine the importance of matrix effects. A correlation between the variation of the relative sensitivity coefficients (RSC's) and the spark plasma composition, hence plasma temperature, was found. The determined RSC's were used in the analysis of four biological standard reference materials. An accuracy of 1013% and detection limits between 0.005 and 0.5 ppm were obtained during analysis under normal conditions.