Publication
Title
Increased erythrocyte glutathione peroxidase activity in psoriatics consuming high-selenium drinking water at the dead-sea psoriasis treatment center
Author
Abstract
Erythrocyte selenium-dependent glutathione peroxidase activity was measured in psoriatic Danes, before and after their four-week balneological therapy at the Ein-Bokek International Psoriasis Treatment Center, on the Dead-Sea shore in Israel. The drinking water in Ein-Bokek was found to be rich in selenium, a trace element with anticarcinogenic properties and of great importance in human nutrition and health. The most reliable biological parameter for increase in selenium bioavailability is the erythrocytes' glutathione-peroxidase activity. As psoriasis is a proliferative skin disease, the activity of this enzyme was assayed in 35 psoriatic Danes and in 25 long-term local hotel workers, as well as in 34 volunteers drinking low-selenium water. The glutathione peroxidase activity in the psoriatic patients increased significantly during their four-week stay in Ein-Bokek. Erythrocyte glutathione peroxidase activity in the hotel workers was 50% higher than that in the healthy volunteers consuming low-selenium water. A possible role of selenium in psoriasis is suggested.
Language
English
Source (journal)
Pharmacological research communications. - London
Publication
London : 1985
ISSN
0031-6989
Volume/pages
17:5(1985), p. 479-488
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
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Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
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Record
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Creation 08.05.2014
Last edited 23.12.2015
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