Publication
Title
Ultrastructural localization of aluminium in liver of aluminium maltol-treated rabbits by laser microprobe mass analysis
Author
Abstract
By means of laser microprobe mass analysis (LAMMA), we have studied the ultrastructural localization of aluminium in livers of aluminium maltol-treated rabbits. This animal model was developed to study long-term aluminium toxicity using systemic (intravenous) administration of aluminium. We could only detect aluminium in electron-dense inclusion bodies found in large, sometimes multinucleated cells. These results prove that the actual observation of aluminium deposits in liver with LAMMA gives more information than bulk analysis and can be very useful to explore mechanisms of toxicity.
Language
English
Source (journal)
Biomedical and environmental mass spectrometry. - London, 1986 - 1990
Publication
London : 1989
ISSN
0887-6134
Volume/pages
18:8(1989), p. 598-602
Full text (Publishers DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Record
Identification
Creation 09.05.2014
Last edited 22.11.2016
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