Recovery of peripheral muscle function from fatiguing exercise and daily physical activity level in patients with multiple sclerosis : a case-control studyRecovery of peripheral muscle function from fatiguing exercise and daily physical activity level in patients with multiple sclerosis : a case-control study
Faculty of Medicine and Health Sciences
Translational Neurosciences (TNW)
Rehabilitation Sciences and Physiotherapy (REVAKI)
Clinical neurology and neurosurgery. - Assen
122(2014), p. 97-105
University of Antwerp
Objectives Delayed recovery of muscle function following exercise has been demonstrated in the lower limbs of patients with multiple sclerosis (MS). However, studies examining this in the upper limbs are currently lacking. This study compared physical activity level (PAL) and recovery of upper limb muscle function following exercise between MS patients and healthy inactive controls. Furthermore, the relationship between PAL and muscle recovery was examined. Methods PAL of 19 MS patients and 32 controls was measured using an accelerometer for 7 consecutive days. Afterwards, recovery of muscle function was assessed by performing a fatiguing upper limb exercise test with subsequent recovery measures. Results Muscle recovery of the upper limb muscles was similar in both groups. Average activity counts were significantly lower in MS patients than in the control group. MS patients spent significantly more time being sedentary and less time on activities of moderate intensity compared with the control group. No significant correlation between PAL and recovery of muscle function was found in MS patients. Conclusions Recovery of upper limb muscle function following exercise is normal in MS patients. MS patients are less physically active than healthy inactive controls. PAL and recovery of upper limb muscle function appear unrelated in MS patients.