Publication
Title
Extremely elevated cerebrospinal fluid protein levels in a child with neurologic symptoms : beware of haemophagocytic lymphohistiocytosis
Author
Abstract
Neurologic symptoms can be the initial manifestation of haemophagocytic lymphohistiocytosis (HLH). In this case study, we present a 3-year old boy with a clinical picture of encephalitis, a cerebrospinal fluid (CSF) protein level up to 1165 mg/dl and diffuse cerebral MRI abnormalities. The diagnosis of HLH was established only 6 weeks after initial presentation. The boy recovered after HLH therapy with persisting mild cognitive defects. Genetic investigation demonstrated X-linked lymphoproliferative disease (XLP) as the underlying cause of HLH. The extremely elevated protein level in CSF in this case has not yet been reported in patients with HLH. (C) 2013 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.
Language
English
Source (journal)
European journal of paediatric neurology. - London
Publication
London : 2014
ISSN
1090-3798
Volume/pages
18:3(2014), p. 427-429
ISI
000336695500027
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 03.07.2014
Last edited 05.12.2017
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