Title
MRI/PET brain imaging MRI/PET brain imaging
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
bookPart
Publication
Berlin :Springer, [*]
Subject
Physics
Human medicine
Source (book)
PET and SPECT in neurology / Dierckx, Rudi A.J.O. [edit.]; et al.
ISBN - Hoofdstuk
978-3-642-54307-4
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Multimodalbrain imaging has become an established clinical and research tool for diagnosis and disease progression of brain disorders. Among available imaging modalities, magnetic resonance imaging (MRI) and positron emission tomography (PET) can provide a wide spectrum of data for the in vivo mapping of neurobiological functions and brain morphology while demonstrating to relationships between behavioral and neurobiological factors. Since MRI mostly uses endogenous contrast mechanisms to visualize and quantify tissue characteristics, optimal sequence design is essential for the diagnostic information of MRI. On the other hand, PET imaging is always based on the exogenous contrast of an injected PET tracer. Therefore, characteristics of the PET tracer determine the quantitative and diagnostic potential of PET. This chapter will focus on both of these modalities and shortly discuss the potential of multimodal or hybrid MR/PET imaging. We will not cover MR spectroscopy nor specific applications of H2 15O PET since this will be discussed in other chapters of this book.
Handle