Title
Unusual 2(1H)-pyrazinones isolated from a culture of a Brazilian marine-derived streptomyces sp. Unusual 2(1H)-pyrazinones isolated from a culture of a Brazilian marine-derived streptomyces sp.
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Publication type
article
Publication
Subject
Pharmacology. Therapy
Source (journal)
NATURAL PRODUCT COMMUNICATIONS
Volume/pages
9(2014) :9 , p. 1275-1278
ISSN
1934-578X
ISI
000342546200013
Carrier
E
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and FIRMS. The application of this system to identify, purify and elucidate all the structures is described.
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