Unusual 2(1H)-pyrazinones isolated from a culture of a Brazilian marine-derived streptomyces sp.
do Nascimento, Eduardo S. P.
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
NATURAL PRODUCT COMMUNICATIONS
, p. 1275-1278
University of Antwerp
Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and FIRMS. The application of this system to identify, purify and elucidate all the structures is described.