Extending the scope of the Aza-Fischer synthesis of 4- and 6-azaindolesExtending the scope of the Aza-Fischer synthesis of 4- and 6-azaindoles
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Medicinal Chemistry (UAMC)
European journal of organic chemistry. - Weinheim
(2013):16, p. 3328-3336
Fischer indole cyclization has recently been described as an efficient approach to the synthesis of azaindoles bearing electron-donating groups. We now show that this cascade reaction can be very efficient for the formation of a wider range of 4- and 6-azaindoles by using microwave irradiation.