Synthesis of thiophene analogues of the tacrine seriesSynthesis of thiophene analogues of the tacrine series
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Synthesis: journal of synthetic organic chemistry. - Stuttgart
(2007):7, p. 1027-1032
3-Amino-2-cyanothiophenes condensed with cyclanones and afforded analogues of Velnacrine in two or three steps. Condensation under Friedländers conditions gave tacrine analogues in one step.