Publication
Title
Fatal outcome of a hypersensitivity reaction to paclitaxel : a critical review of premedication regimens
Author
Abstract
Hypersensitivity reactions (HSRs) to paclitaxel are frequently encountered in patients receiving this antitumour drug. Administration of histamine H1- and H2-receptor antagonists and corticosteroids has been shown to reduce significantly the risk of developing an HSR in patients receiving taxanes. In this case report, we describe the fatal outcome of an HSR in a patient receiving paclitaxel despite short-course premedication. the level of evidence supporting the short-course i.v. premedication schedule is challenged, as it is not compatible with the pharmacokinetic properties of dexamethasone.
Language
English
Source (journal)
The British journal of cancer. - London
Publication
London : 2004
ISSN
0007-0920
Volume/pages
90:2(2004), p. 304-305
ISI
000189010600005
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 18.11.2014
Last edited 18.07.2017