Publication
Title
Organohalogenated contaminants (OHCs) in human serum of mothers and children from Pakistan with urban and rural residential settings
Author
Abstract
This study aimed to provide first data on the concentrations of different classes of organohalogenated contaminants (OHCs) in human serum from Pakistan, an area with limited information on environmental pollution. Serum samples (N = 85) were collected from mothers (N = 34; age ranged 23-51 years), their children (N = 34; age 3-10 years) and general group (N = 17; age 13-65 years) with rural and urban residential settings. The concentrations of studied OHCs in serum decreased as follows: organochlorinated pesticides (OCPs) > polychlorinated biphenyls (PCBs) > polybrominated diphenyl ethers (PBDEs). Novel brominated flame retardants (NBFRs) were not detected, except for 1,2-bis(2,4,6-tribromophenoxy)-ethane (BTBPE) < 0.2-8 ng/g lipid weight (lw). Low levels of HO-PCBs (<0.2-20 ng/g lw) were detected, while HO-PBDEs were <0.2 ng/g lw. Sigma PCBs (2-105 ng/g lw) together with Sigma PBDEs (0.2-6.7 ng/g lw) contributed similar to 5% of the total OHCs body burden. The concentration(s) of major contributors (>80%) of OCPs ranged from <1-3645 ng/g lw for 1,1'-bis-(4-chlorophenyl)-2,2-dichloroethene (p,p'-DDE), <1-445 ng/g lw for p-hexachlorocyclohexane (beta-HCH) and from 5 to 200 ng/g lw for pentachlorophenol (PCP). p,p'-DDE, the major OHC, was significantly higher (p < 0.05) in rural children than in all other groups. In serum of rural children, the major OHCs were significantly higher (p < 0.05) than the mothers. The current study indicates continuous exposure to humans with already regulated OHCs and highlights the need for further monitoring of these OHCs in the region. (C) 2013 Elsevier B.V. All rights reserved.
Language
English
Source (journal)
The science of the total environment. - Amsterdam
Publication
Amsterdam : 2013
ISSN
0048-9697
Volume/pages
461(2013), p. 655-662
ISI
000323851500068
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 04.12.2014
Last edited 11.07.2017
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