Publication
Title
VariantDB : a flexible annotation and filtering portal for next generation sequencing data
Author
Abstract
Interpretation of the multitude of variants obtained from next generation sequencing (NGS) is labor intensive and complex. Web-based interfaces such as Galaxy streamline the generation of variant lists but lack flexibility in the downstream annotation and filtering that are necessary to identify causative variants in medical genomics. To this end, we built VariantDB, a web-based interactive annotation and filtering platform that automatically annotates variants with allele frequencies, functional impact, pathogenicity predictions and pathway information.
Language
English
Source (journal)
Genome medicine
Publication
2014
ISSN
1756-994X
Volume/pages
6(2014), 10 p.
Article Reference
74
ISI
000344570700001
Medium
E-only publicatie
Full text (Publishers DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 10.12.2014
Last edited 07.03.2017
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