Title
CPAP washout prior to reevaluation polysomnography : a sleep surgeon's perspective CPAP washout prior to reevaluation polysomnography : a sleep surgeon's perspective
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Berlin ,
Subject
Human medicine
Source (journal)
Sleep and breathing. - Berlin
Volume/pages
19(2015) :2 , p. 433-439
ISSN
1520-9512
ISI
000352909700002
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Purpose Obstructive sleep apnea (OSA) is characterized by repetitive upper airway collapse during sleep, leading to decreased oxygen blood levels and arousal from sleep. The gold standard treatment option for moderate to severe OSA is considered continuous positive airway pressure (CPAP). In case primary treatment with CPAP fails, a reevaluation of disease severity [by means of the apnea/hypopnea-index (AHI)] can be required. A subset of patients that prefer a CPAP alternative is still using CPAP until the reevaluation polysomnography (PSG), and a so-called washout effect is not ruled out. The purpose of this study is to evaluate the evidence on the existence and duration of this washout effect and its clinical relevance for current practice. Methods To identify papers for this review, an extensive literature search was run electronically through MEDLINE and EMBASE databases. Results An overview of currently available literature on this washout effect and the findings of 13 studies on this topic are discussed. Conclusion There is some evidence that CPAP washout exists in patients with a stable BMI throughout the follow-up period. However, the intensity and duration of this effect remains unclear. Within the limitations of the present study, it seems reasonable to maintain a washout period of 1 week, in case alternative treatments options are considered and especially when a baseline PSG (and subsequent repeat PSG after treatment) is needed in case of clinical trials.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/eb010d/9276.pdf
E-info
https://repository.uantwerpen.be/docman/iruaauth/476ebd/121356.pdf
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