Title
Recurrent leishmaniasis in kidney transplant recipients: report of 2 cases and systematic review of the literature Recurrent leishmaniasis in kidney transplant recipients: report of 2 cases and systematic review of the literature
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Copenhagen ,
Subject
Human medicine
Source (journal)
Transplant infectious disease. - Copenhagen
Volume/pages
13(2011) :4 , p. 397-406
ISSN
1398-2273
ISI
000293658000011
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed.
E-info
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