Publication
Title
Bortezomib : a new player in pre- and post-transplant desensitization?
Author
Abstract
Several desensitization strategies have been investigated for the reversal of acute antibody-mediated rejection or for the removal of preformed anti-HLA antibodies, with the aim to promote access to renal transplantation. Today, their success appears limited or incomplete. Bortezomib, a selective inhibitor of the 26S proteasome, which is largely used in the treatment of multiple myeloma, could be a novel promising desensitizing agent. Its mechanism of action and preliminary clinical use in renal transplantation is reviewed here.
Language
English
Source (journal)
Nephrology, dialysis, transplantation. - Berlin
Publication
Oxford : Oxford univ press, 2010
ISSN
0931-0509
Volume/pages
25:11(2010), p. 3480-3489
ISI
000283683900006
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 06.01.2015
Last edited 19.06.2017