Publication
Title
Thrombophilic factors do not predict outcomes in renal transplant recipients under prophylactic acetylsalicylic acid
Author
Abstract
The rate of thromboembolic events or acute rejection episodes during the first posttransplant year (primary composite endpoint) was 16.7% among patients free of thrombophilic factor (N = 60) and 17.2% in those with >= 1 thrombophilic factor (N = 250) (p > 0.99). The incidence of the primary endpoint was similar among patients free of thrombophilic factors and those with >= 2 (N = 135), or >= 3 (N = 53) factors (16.3% and 15.1% respectively; p = 1) and in patients who remained thrombophilic at 1 month (15.7%; p = 0.84). None of the individual thrombophilic factor present at the day of transplantation was associated with the primary endpoint. The incidence of cardiovascular events at 1-year, serum creatinine at 1-year, 4-year actuarial graft and patient survival were not influenced by the presence of >= 1 thrombophilic factor at baseline (p = NS). In conclusion, the presence of thrombophilic factors does not influence thromboembolic events, acute rejection, graft or patient survival in patients transplanted after 2000 and receiving prophylactic acetylsalicylic acid.
Language
English
Source (journal)
American journal of transplantation. - Copenhagen
Publication
Copenhagen : 2010
ISSN
1600-6135
Volume/pages
10:1(2010), p. 99-105
ISI
000272882000016
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
[E?say:metaLocaldata.cgzprojectinf]
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 06.01.2015
Last edited 02.08.2017