Publication
Title
Sulfadiazine-induced obstructive renal-failure in a kidney-transplant recipient
Author
Abstract
A kidney transplant recipient on long-term sulfadiazine and pyrimethamine therapy for recurrent toxoplasmosis chorioretinitis developed acute oliguric renal failure. Ultrasound examination of the graft revealed hydronephrosis caused by radiolucent calculi. The calculi were most probably made of sulfadiazine, as sulfadiazine crystalluria was detected on several occasions prior to the acute obstruction. Although percutaneous nephrostomy was temporarily required, withdrawal of sulfadiazine and alkalinization of the urine led to a prompt dissolution of the calculi. The risks factors and therapeutic measures of sulfadiazine-induced obstructive nephropathy are reviewed.
Language
English
Source (journal)
Clinical transplantation. - New York
Publication
New York : 1992
ISSN
0902-0063
Volume/pages
6:31(1992), p. 191-193
ISI
A1992JB84900009
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 06.01.2015
Last edited 19.07.2017