Title
Individual differences in behavioral flexibility in a probabilistic reversal learning task : an fMRI studyIndividual differences in behavioral flexibility in a probabilistic reversal learning task : an fMRI study
Author
Faculty/Department
Faculty of Applied Economics
Faculty of Medicine and Health Sciences
Research group
Management
Antwerp Surgical Training, Anatomy and Research Centre (ASTARC)
Publication type
article
Publication
Subject
Psychology
Economics
Source (journal)
Journal of neuroscience, psychology, and economics
Volume/pages
7(2014):4, p. 203-218
ISSN
1937-321X
2151-318X
1937-321X
ISI
000348720900002
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Behavioral flexibility is an important aspect of self-regulation and involves effectively learning, unlearning, and relearning associations between actions and outcome. Using a probabilistic reversal learning paradigm (PRL), the neural correlates of flexibility have previously been associated with brain regions implicated in cognitive control, including the anterior cingulate cortex (ACC) and lateral prefrontal cortex, and with the nucleus accumbens (Nacc) implicated in reward. The current study on healthy young males (n = 40) extends this previously published work in 3 ways. First we corroborate the involvement of ACC, VLPFC, and DLPFC at the exact moment of behavioral switches. Second, we report increased activation of the dACC and caudate head with increasing number of perseverating errors preceding a behavioral switch. Third, better performance on the task is associated with increased activation of rACC and VLPFC during switching, suggesting that these regions contribute to individual differences in behavioral flexibility. These findings cannot be extended to individual differences in a self-reported measure of self-regulation.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/1f3440/9212.pdf
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