Title
Non-small cell lung cancer : when to offer sublobar resection Non-small cell lung cancer : when to offer sublobar resection
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Clare :Elsevier ireland ltd ,
Subject
Human medicine
Source (journal)
Lung cancer: journal of the International Association for the Study of Lung Cancer / International Association for the Study of Lung Cancer [Aurora, Colo.] - Amsterdam
Volume/pages
86(2014) :2 , p. 115-120
ISSN
0169-5002
ISI
000344438400001
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Sublobar resection for lung cancer - whether non-anatomic wedge resection or anatomic segmentectomy - has emerged as a credible alternative to lobectomy for the surgical treatment of selected patients with lung cancer. Sublobar resection promises to cause less pulmonary compromise in such patients. Emerging evidence suggests that sublobar resection may offer survival outcomes approaching that of lobectomy for lung cancer patients whose disease meets the following criteria: stage IA disease only; tumor up to 2-3 cm diameter; peripheral location of tumor in the lung; and predominantly ground-glass (non-solid) appearance on CT imaging. The best results are obtained with segmentectomy (as opposed to wedge resection) and complete lymph node dissection. Nevertheless, the evidence is currently still limited, and the above criteria are met only in a minority of patients. Large randomized trials are underway to define the clinical role of sublobar resections, and results are eagerly anticipated. Until that time, lobectomy should still be regarded as the mainstay of surgical therapy for patients with early stage lung cancer at present. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
E-info
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