Title
Strengths, weaknesses, and opportunities of diagnostic breathomics in pleural mesothelioma-A hypothesis Strengths, weaknesses, and opportunities of diagnostic breathomics in pleural mesothelioma-A hypothesis
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Baltimore, Md ,
Subject
Human medicine
Source (journal)
Cancer epidemiology, biomarkers and prevention / American Association for Cancer Research. - Baltimore, Md
Volume/pages
23(2014) :6 , p. 898-908
ISSN
1055-9965
ISI
000345270800002
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Past and present asbestos use will reflect in increasing numbers of mesothelioma cases in the next decades, diagnosed at a late stage and with a dismal prognosis. This stresses the need for early detection tools, which could improve patients' survival. Recently, breath analysis as a noninvasive and fast diagnostic tool has found its way into biomedical research. High-throughput breathomics uses spectrometric, chromatographic, and sensor techniques to diagnose asbestos-related pulmonary diseases based upon volatile organic compounds (VOC) in breath. This article reviews the state-of-the-art available breath analyzing techniques and provides the insight in the current use of VOCs as early diagnostic or prognostic biomarkers of mesothelioma to stimulate further research in this field. (C) 2014 AACR.
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https://repository.uantwerpen.be/docman/iruaauth/39042a/5e0122152.pdf
Handle