Title
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Overview of the repeatability, reproducibility, and agreement of the biometry values provided by various ophthalmic devices
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Author
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Abstract
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PURPOSE: To present an overview of the measurement errors for various biometric devices, as well as a meta-analysis of the agreement between biometric devices using the Pentacam, Orbscan, and IOL Master as a reference. DESIGN: Meta-analysis of the literature. METHODS: The meta-analysis is based on data from 216 articles that compare a total of 24 different devices with the reference devices for the following 9 parameters: mean, steep and flat curvature of the anterior and posterior cornea; central corneal thickness; anterior chamber depth; and axial length. After the weighted average difference between devices has been determined, the "two one-sided t test" was used to test for equivalence between devices within certain thresholds defined by the measurement errors and the influence of these differences on the calculated refraction. RESULTS: In only 17 of the 70 comparisons a device was equivalent with the reference device within the thresholds set by the measurement error. More lenient thresholds, based on a change in calculated refraction of +/- 0.25 diopter, increased this number to a maximum of 25/50 comparisons (excluding pachymetry). High degrees of inconsistency were seen in the reported results, which could partially explain the low agreement between devices. CONCLUSION: As a rule, biometry measurements taken by different devices should not be considered equivalent, although several exceptions could be identified. We therefore recommend that clinical studies involving multiple device types treat this as a within-subject variable to avoid bias. The follow-up of individual patients using different devices should be avoided at all times. (C) 2014 by Elsevier Inc. All rights reserved. |
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Language
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English
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Source (journal)
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American journal of ophthalmology. - Chicago, Ill.
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Publication
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Chicago, Ill.
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2014
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ISSN
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0002-9394
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DOI
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10.1016/J.AJO.2014.08.014
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Volume/pages
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158
:6
(2014)
, p. 1111-1120
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ISI
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000345820400004
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Pubmed ID
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25128596
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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