Publication
Title
Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage
Author
Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) emerged in the late 1980s and rapidly became one of the most significant viral pathogens in the swine industry. In vivo, the virus shows a very narrow cell tropism and targets specific subsets of porcine macrophages. The entry of PRRSV into its host cell is the first crucial step in infection and has been the focus of many fundamental studies. This review provides a comprehensive overview of the current knowledge on PRRSV entry into the porcine macrophage, covering virus binding, internalization and genome release, and integrates these findings into a general model of the entry process.
Language
English
Source (journal)
Journal of general virology. - London
Publication
London : 2010
ISSN
0022-1317
Volume/pages
91:7(2010), p. 1659-1667
ISI
000279747600001
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 16.01.2015
Last edited 11.07.2017