Title
Liquid biopsies in lung cancer : the new ambrosia of researchers Liquid biopsies in lung cancer : the new ambrosia of researchers
Author
Faculty/Department
Faculty of Sciences. Biology
Faculty of Sciences. Chemistry
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Amsterdam :Elsevier science bv ,
Subject
Physics
Chemistry
Biology
Human medicine
Source (journal)
Biochimica et biophysica acta : CR : reviews on cancer. - Amsterdam
Volume/pages
1846(2014) :2 , p. 539-546
ISSN
0304-419X
ISI
000347263400022
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
In the last decades the approach to cancer patient management has been deeply revolutionized. We are moving from a "one-fits-all" strategy to the "personalized medicine" based on the molecular characterization of the tumor. In this new era it is becoming more and more clear that the monitoring of the disease is fundamental for the success of the treatment, thus there is the need of new biomarker discovery. More precisely in the last years the scientific community has started to use the term "liquid biopsy". A liquid biopsy is a liquid biomarker that can be easily isolated from many body fluids (blood, saliva, urine, ascites, pleural effusion, etc.) and, as well as a tissue biopsy, a representative of the tissue from which it is spread. In this review we will focus our attention on circulating tumor cells, circulating tumor DNA, exosomes and secretomes with the aim to underlie their usefulness and potential application in a clinical setting for lung cancer patient management. (C) 2014 Elsevier B.V. All rights reserved.
E-info
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