Publication
Title
Liquid biopsies in lung cancer : the new ambrosia of researchers
Author
Abstract
In the last decades the approach to cancer patient management has been deeply revolutionized. We are moving from a "one-fits-all" strategy to the "personalized medicine" based on the molecular characterization of the tumor. In this new era it is becoming more and more clear that the monitoring of the disease is fundamental for the success of the treatment, thus there is the need of new biomarker discovery. More precisely in the last years the scientific community has started to use the term "liquid biopsy". A liquid biopsy is a liquid biomarker that can be easily isolated from many body fluids (blood, saliva, urine, ascites, pleural effusion, etc.) and, as well as a tissue biopsy, a representative of the tissue from which it is spread. In this review we will focus our attention on circulating tumor cells, circulating tumor DNA, exosomes and secretomes with the aim to underlie their usefulness and potential application in a clinical setting for lung cancer patient management. (C) 2014 Elsevier B.V. All rights reserved.
Language
English
Source (journal)
Biochimica et biophysica acta : CR : reviews on cancer. - Amsterdam
Publication
Amsterdam : Elsevier science bv, 2014
ISSN
0304-419X
Volume/pages
1846:2(2014), p. 539-546
ISI
000347263400022
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 04.02.2015
Last edited 21.05.2017
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