Title
Anaphylaxis to succinylated gelatin in a patient with a meat allergy: galactose-alpha(1,3)-galactose (alpha-gal) as antigenic determinant Anaphylaxis to succinylated gelatin in a patient with a meat allergy: galactose-alpha(1,3)-galactose (alpha-gal) as antigenic determinant
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Stoneham, Mass. ,
Subject
Human medicine
Source (journal)
Journal of clinical anesthesia. - Stoneham, Mass.
Volume/pages
26(2014) :7 , p. 574-576
ISSN
0952-8180
ISI
000346222400011
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Specific immunoglobulin E (sIgE) antibodies towards the galactose-alpha(1,3)-galactose (alpha-gal) moieties may elicit life-threatening and fatal anaphylactic reactions. Patients sensitized to alpha-gal moieties from mammalian meat may also react towards mammalian gelatins and gelatin-containing drugs such as bovine gelatin-based colloid plasma substitute. The case of a 56 year old woman with a meat allergy who suffered anaphylaxis to succinylated gelatin is reported. (C) 2014 Elsevier Inc. All rights reserved.
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