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Title
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Bioaccumulation of hydroxylated polychlorinated biphenyls and pentachlorophenol in the serum of northern elephant seal pups (Mirounga angustirostris)
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Author
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Abstract
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| Northern elephant seals (NES) (Mirounga angustirostris) from the A (n) over tildeo Nuevo State Reserve (CA, USA) were sampled at 1-, 4-, 7- and 10-week post-weaning. Concentrations of hydroxylated polychlorinated biphenyls (HO-PCBs) and their parent PCBs were measured in the serum of each individual. The Sigma HO-PCB concentrations in the serum increased significantly between early and late fast (from 282 +/- 20 to 529 +/- 31 pg/mL). This increase might result from a mobilisation of HO-PCBs transferred from the mother during gestation and/or lactation and stored in the pup's liver. Food deprivation has been shown to exacerbate biotransformation capacities in mammals, birds and fish. The HO-penta-CBs was the predominant homologue group, followed by HO-hexa-CBs and HO-hepta-CBs. No preferential pathway for the metabolism of HO-PCBs (HO-direct insertion or NIH-shift of a chlorine atom) could be evidenced. The concentrations of pentachlorophenol (PCP) in the serum of weaned NES increased from 103 +/- 7 pg/mL at early fast to 246 +/- 41 pg/mL at late fast, which is within the range of PCP concentrations usually encountered in marine mammals. (C) 2014 Elsevier Inc. All rights reserved. |
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Language
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English
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Source (journal)
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Environmental research. - Amsterdam, 1967, currens
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Publication
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Amsterdam
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Elsevier
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2015
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ISSN
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0013-9351
[print]
1096-0953
[online]
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DOI
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10.1016/J.ENVRES.2014.08.040
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Volume/pages
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136
(2015)
, p. 441-448
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ISI
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000346755000054
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Pubmed ID
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25460666
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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