Publication
Title
Decorrelated neuronal firing in cortical microcircuits
Author
Abstract
Correlated trial-to-trial variability in the activity of cortical neurons is thought to reflect the functional connectivity of the circuit. Many cortical areas are organized into functional columns, in which neurons are believed to be densely connected and to share common input. Numerous studies report a high degree of correlated variability between nearby cells. We developed chronically implanted multitetrode arrays offering unprecedented recording quality to reexamine this question in the primary visual cortex of awake macaques. We found that even nearby neurons with similar orientation tuning show virtually no correlated variability. Our findings suggest a refinement of current models of cortical microcircuit architecture and function: Either adjacent neurons share only a few percent of their inputs or, alternatively, their activity is actively decorrelated.
Language
English
Source (journal)
Science / American Association for the Advancement of Science [Washington, D.C.] - Washington, D.C.
Publication
Washington, D.C. : 2010
ISSN
0036-8075
1095-9203
Volume/pages
327:5965(2010), p. 584-587
ISI
000274020500039
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 07.02.2015
Last edited 21.06.2017