Title
The changes in left ventricular structure-function relationship in aortic valve stenosis The changes in left ventricular structure-function relationship in aortic valve stenosis
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
Subject
Human medicine
Source (journal)
OA anatomy
Volume/pages
2(2014) :3 , p. 1-5
ISSN
2052-7829
Article Reference
24
Carrier
E-only publicatie
Target language
English (eng)
Affiliation
University of Antwerp
Abstract
Introduction AVR in patients with calcified aortic valve stenosis relieves the left ventricle from pressure overload. Yet, congestive heart failure (CHF) is one of the complications observed, even years after the operation. The main questions are: why do patients still develop CHF? Which types of CHF can be expected? Which predictors are known? Discussion It has become clear that decrease in ejection fraction, which is the most commonly used parameter, occurs late in the course of aortic valve stenosis, when damage to the left ventricle has already been inflicted on this cardiac cavity. Several more sensitive imaging and Doppler parameters can demonstrate this damage earlier in the course of CAVS. This damage proves to be irreversible, at least in part. This explains the appearance of heart failure after aortic valve replacement. Although this type of heart failure is diastolic in nature, a continuum with the systolic type probably exists, at least in patients with aortic valve stenosis. Conclusions Damage to the left ventricle in patients with aortic valve stenosis can go unnoticed if only ejection fraction is used as parameter. Detection of more subtle changes, even in asymptomatic patients with severe aortic valve stenosis might lead to early replacement and hence less postoperative heart failure.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/980859/fd8ed76b.pdf
Handle