Title
Peptidomics of the locust corpora allata : identification of novel pyrokinins (-FXPRLamides) Peptidomics of the locust corpora allata : identification of novel pyrokinins (-FXPRLamides)
Author
Faculty/Department
Faculty of Sciences. Biology
Publication type
article
Publication
Fayetteville, N.Y. ,
Subject
Chemistry
Biology
Pharmacology. Therapy
Source (journal)
Peptides. - Fayetteville, N.Y.
Volume/pages
24(2003) :10 , p. 1493-1500
ISSN
0196-9781
ISI
000188259000006
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Abstract
The peptidomes of the corpora allata of Locusta migratoria and Schistocerca gregaria were investigated by both matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and nanoscale liquid chromatography quadrupole time-of-flight tandem mass spectrometry (nanoLC-Q-TOF MSMS). The pyrokinin (-FXPRLamide) family seems to be predominant. In addition to the known pyrokinins, we de novo sequenced four pyrokinins in L migratoria and five in S. gregaria. In addition, one pyrokinin-like peptide (-PRLamide) was identified in S. gregaria. Besides the -(FX)PRLamides, FLRFamide-l, the allatostatins (A family) and numerous as yet unidentified peptides are also present in the corpora allata. (C) 2003 Elsevier Inc. All rights reserved.
E-info
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