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Title
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Peptidomics of the pars intercerebralis-corpus cardiacum complex of the migratory locust, **Locusta migratoria**
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Author
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Abstract
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| The pars intercerebralis-corpora cardiaca system (PI-CC) of insects is the endocrinological equivalent of the hypothalamus-pituitary system of vertebrates. Peptide profiles of the pars intercerebralis and the corpora cardiaca were characterized using simple sampling protocols in combination with MALDI-TOF and electrospray ionization double quadrupole time of flight (ESI-Qq-TOF) mass spectrometric technologies. The results were compared with earlier results of conventional sequencing methods and immunocytochemical methods. In addition to many known peptides, several m/z signals corresponding to putative novel peptides were observed in the corpora cardiaca and/or pars intercerebralis. Furthermore, for a number of peptides evidence was provided about their localization and MALDI-TOF analysis of the released material from the corpora cardiaca yielded information on the hormonal status of particular brain peptides. |
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Language
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English
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Source (journal)
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European journal of biochemistry. - Berlin
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Publication
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Berlin
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2001
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ISSN
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0014-2956
[print]
1432-1033
[online]
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DOI
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10.1046/J.1432-1327.2001.02067.X
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Volume/pages
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268
:7
(2001)
, p. 1929-1939
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ISI
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000168004300004
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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