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Title
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Phytochemical characterisation of a cytotoxic stem bark extract of **Steganotaenia araliacea** and identification of a protoflavanone by LCSPENMR
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Author
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Abstract
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| A 80% ethanolic stem bark extract of Steganotaenia araliacea (Apiaceae) showed cytotoxic properties against MDA-MB-231 (breast), PANC-1 (pancreas) and HT-29 (colon) cancer cell lines. Phytochemical investigations by LC-SPE-NMR led to the identification of spiropreussomerin A, most probably produced by an endophytic fungus, the flavanonol conrauiflavonol / afzelin A, and a protoflavanone that has not been reported before and for which the name steganoprotoflavanone was adopted. Surprisingly none of the previously reported cytotoxic dibenzocyclo-octadiene lactone lignans was obtained as a major constituent of the cytotoxic extract. |
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Language
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English
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Source (journal)
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Phytochemistry letters
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Publication
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2015
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ISSN
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1874-3900
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DOI
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10.1016/J.PHYTOL.2015.03.008
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Volume/pages
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12
(2015)
, p. 119-124
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ISI
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000356336400022
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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