Publication
Title
The effect of human follicular fluid on bovine oocyte developmental competence and embryo quality
Author
Abstract
In this study, the hypothesis that embryo development during routine IVF procedures is determined by the pre-ovulatory follicular fluid composition was tested. Follicular fluid from women with obesity (obese) and a positive or negative IVF outcome was added during the in-vitro maturation of bovine oocytes. Negative and obese follicular fluid reduced bovine embryo development, compared with laboratory control embryo development (P < 0.05 or P < 0.1). The addition of follicular fluid also altered bovine blastocyst gene expression. Furthermore, LDHA and PPARGC1B gene expression differed between follicular fluid groups. Data suggest that pre-ovulatory follicular fluid can potentially affect oocyte developmental competence and embryo quality. Furthermore, the bovine model may be used as a screening tool.
Language
English
Source (journal)
Reproductive biomedicine online. - Cambridge
Publication
Cambridge : 2015
ISSN
1472-6483
Volume/pages
30:2(2015), p. 203-207
ISI
000349087000015
Full text (Publisher's DOI)
Full text (open access)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 02.04.2015
Last edited 07.09.2017
To cite this reference