Title
Development of a novel in vitro onychomycosis model for the evaluation of topical antifungal activity Development of a novel in vitro onychomycosis model for the evaluation of topical antifungal activity
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences. Pharmacy
Publication type
article
Publication
Amsterdam ,
Subject
Chemistry
Biology
Human medicine
Source (journal)
Journal of microbiological methods. - Amsterdam
Volume/pages
112(2015) , p. 73-75
ISSN
0167-7012
ISI
000353426900014
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
A novel in vitro onychomycosis model was developed to easily predict the topical activity potential of novel antifungal drugs. The model encompasses drug activity and diffusion through bovine hoof slices in a single experimental set-up. Results correspond well with the antifungal susceptibility assay and Franz cell diffusion test.
E-info
https://repository.uantwerpen.be/docman/iruaauth/9165f0/65dbc0bb885.pdf
Full text (open access)
https://repository.uantwerpen.be/docman/irua/e3972d/9775.pdf
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