Publication
Title
Cardiac endothelium-myocyte interaction : clinical opportunities for new heart failure therapies regardless of ejection fraction
Author
Abstract
Heart failure (HF) is an important global health problem with great socioeconomic burden. Outcomes remain sub-optimal. Endothelium cardiomyocyte interactions play essential roles in cardiovascular homeostasis, and deranged endothelium-related signalling pathways have been implicated in the pathophysiology of HF. In particular, disturbances in nitric oxide (NO)-mediated pathway and neuregulin-mediated pathway have been shown to contribute to the development of HF. These signalling pathways hold the potential as pathophysiological targets for new HF therapies, and may aid in patient selection for future HF trials.
Language
English
Source (journal)
European heart journal. - London
Publication
London : 2015
ISSN
0195-668X [Print]
1522-9645 [Online]
Volume/pages
36:31(2015), p. 2050-+
ISI
000360619200015
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 29.04.2015
Last edited 17.11.2017
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