Resident and nurse reports of potential adverse drug reactions
Faculty of Medicine and Health Sciences
European journal of clinical pharmacology. - Berlin
, p. 741-749
University of Antwerp
Purpose Nursing home residents are at high risk for adverse drug reactions (ADR). To improve pharmacotherapeutic care for individual residents, healthcare professionals need to be aware of ADRs. In nursing homes, nurses have a central role in monitoring residents health and informing physicians on the presence of ADRs. The aim of this study was to evaluate the value of nursing home residents ADR reports. Methods Residents of a convenient sample of two nursing homes were included if their mental status and understanding of Dutch enabled them to report ADRs. In a cross-sectional design, residents and nurses were questioned about 17 potential ADRs. Reports of residents and nurses were consequently compared. Medication use was studied to describe the risk for ADRs per resident. Results Residents had a mean of eight different chronic medication prescriptions. Over 90 % of the residents used medications which increase the risk of feeling somnolent/tired/sedated, arrhythmias and abdominal pain. The median number of potential ADRs reported by nurses was significantly lower compared to the number of resident reports (median [range], respectively, 1  and 4 ). In general, residents reported the presence of more ADRs than nurses, except for confusion. The correspondence between nurse and resident reports ranged from 43 % (dry mouth) till 88 % (arrhythmia). Conclusions Nurses and patients reported a lot of potential ADRs. The type of ADRs they reported was different and complementary. Questioning residents about specific potential ADRs may increase the awareness of ADRs.