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Title
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Hypermobility in patients with chronic fatigue syndrome : preliminary observations
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Author
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Abstract
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| Objective: The present report aims at examining 1. the prevalence of generalized hypermobility in patients with chronic fatigue syndrome [CFS]; 2. whether hypermobile CFS patients experience more pain and have more severe activity limitations/participation restrictions compared to nonhypermobile CFS patients; and 3. whether the history of widespread pain is indicative of generalized hypermobility in patients with CFS. Methods: Forty-four consecutive patients with CFS filled in the Chronic Fatigue Syndrome Activities and Participation Questionnaire [CFS-APQ] for the assessment of activity limitations/ participation restrictions, rated three visual analog scales [for pain, myalgia, and arthralgia], were screened for generalized hypermobility according to the Beighton et al. (1973) criteria, and were questioned about muscle and joint aches. Results: Eleven of the 44 [25 percent] subjects met the criteria for generalized hypermobility. The Spearman Rank correlation analysis did not reveal statistically significant correlations between the Beighton et al. scores and any of the self-reported measures [P > 0.01]. Using the Mann-Whitney U test, no statistically significant differences in pain severity and activity limitations/participation restrictions were observed between hypermobile [N = 11] and nonhypermobile [N = 33] patients with CFS [P > 0.01]. The positive likelihood ratio for widespread pain in shifting the odds favoring the presence of generalized hypermobility was 1.24; the negative likelihood ratio was 0.749. Conclusions: The present report suggests that a subgroup of patients with CFS present with generalized hypermobility, but questions the clinical importance of hypermobility in patients with CFS. A history of widespread pain was not predictive of generalized hypermobility in this sample of CFS patients. |
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Language
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English
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Source (journal)
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Journal of musculoskeletal pain. - Binghamton, NY
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Publication
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Binghamton, NY
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2004
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ISSN
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1058-2452
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DOI
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10.1300/J094V12N01_03
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Volume/pages
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12
:1
(2004)
, p. 9-17
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ISI
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000222268800003
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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