Publication
Title
Hypermobility in patients with chronic fatigue syndrome : preliminary observations
Author
Abstract
Objective: The present report aims at examining 1. the prevalence of generalized hypermobility in patients with chronic fatigue syndrome [CFS]; 2. whether hypermobile CFS patients experience more pain and have more severe activity limitations/participation restrictions compared to nonhypermobile CFS patients; and 3. whether the history of widespread pain is indicative of generalized hypermobility in patients with CFS. Methods: Forty-four consecutive patients with CFS filled in the Chronic Fatigue Syndrome Activities and Participation Questionnaire [CFS-APQ] for the assessment of activity limitations/ participation restrictions, rated three visual analog scales [for pain, myalgia, and arthralgia], were screened for generalized hypermobility according to the Beighton et al. (1973) criteria, and were questioned about muscle and joint aches. Results: Eleven of the 44 [25 percent] subjects met the criteria for generalized hypermobility. The Spearman Rank correlation analysis did not reveal statistically significant correlations between the Beighton et al. scores and any of the self-reported measures [P > 0.01]. Using the Mann-Whitney U test, no statistically significant differences in pain severity and activity limitations/participation restrictions were observed between hypermobile [N = 11] and nonhypermobile [N = 33] patients with CFS [P > 0.01]. The positive likelihood ratio for widespread pain in shifting the odds favoring the presence of generalized hypermobility was 1.24; the negative likelihood ratio was 0.749. Conclusions: The present report suggests that a subgroup of patients with CFS present with generalized hypermobility, but questions the clinical importance of hypermobility in patients with CFS. A history of widespread pain was not predictive of generalized hypermobility in this sample of CFS patients.
Language
English
Source (journal)
Journal of musculoskeletal pain. - Binghamton, NY
Publication
Binghamton, NY : 2004
ISSN
1058-2452
Volume/pages
12:1(2004), p. 9-17
ISI
000222268800003
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 20.05.2015
Last edited 10.05.2017