Publication
Title
Aortic regurgitation after transcatheter aortic valve implantation (TAVI) : angiographic, echocardiographic and hemodynamic assessment in relation to one year outcome
Author
Abstract
Background Aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) remains a relatively frequent and life-limiting complication. However, the most prognostically discriminative (and therefore preferred) technique of AR evaluation after TAVI is not yet clearly defined. The aim of this study was to compare angiographic, echocardiographic and hemodynamic assessment of AR after TAVI in relation to one year outcome. Methods and results In this single center prospective cohort study, angiography (AR grading), echocardiography (AR quantification using color Doppler flow mapping) and invasive hemodynamics (AR index) were assessed before and after TAVI. All patients were followed up to at least one year. A total of 111 consecutive (very) high-risk patients with severe, symptomatic aortic valve stenosis underwent TAVI. No concordant relation could be demonstrated between angiographic, echocardiographic and invasive assessment of AR after TAVI. AR index < 25 post TAVI was significantly influenced by left ventricular posterior wall thickness (odds ratio: 1.276, p = 0.030) and AR index pre TAVI (odds ratio: 0.948, p = 0.019). Neither angiographic nor hemodynamic AR assessments were able to discriminate between good or significantly decreased one year survival. In contrast, color Doppler flow mapping of AR after TAVI was highly reproducible, and able to differentiate between good or significantly decreased one year survival (AR grades 0I: one year survival 87% vs. AR grades IIIIIIV: one year survival 68%, p = 0.035). Conclusion Echocardiography using color Doppler flow mapping is the preferred technique to assess prognostically relevant AR after TAVI.
Language
English
Source (journal)
International journal of cardiology. - Amsterdam, 1981, currens
Publication
Amsterdam : 2015
ISSN
0167-5273
Volume/pages
194(2015), p. 13-20
ISI
000356053900004
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 01.06.2015
Last edited 07.04.2017
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