Publication
Title
Midterm clinical outcome following Edwards SAPIEN or Medtronic Corevalve transcatheter aortic valve implantation (TAVI) : results of the Belgian TAVI registry
Author
Institution/Organisation
Belgian TAVI Registry
Abstract
Objective To assess midterm (3 years) clinical outcomes of transcatheter aortic valve implantation (TAVI) in Belgium using the Edwards SAPIEN valve or the Medtronic CoreValve transcatheter heart valve (THV). Background Medium and long term follow-up data of both THVs are still relatively scarce, although of great clinical relevance for a relatively new but rapidly expanding treatment modality. Therefore, reporting mid- and long term clinical outcome data, coming from large real world national registries, remains contributive. Methods Between December 2007 and March 2012, 861 real world patients who were not candidates for surgical aortic valve replacement as decided by the local heart teams, underwent TAVI at 23 sites. Eleven sites exclusively used SAPIEN THV (n = 460), while 12 exclusively used CoreValve THV (n = 401). Differences in clinical outcomes by valve system were assessed, according to access route and baseline EuroSCORE risk profile (<10%: low, 1020%: intermediate and >20%: high risk). Results Overall cumulative survival at 3 years was 51% for SAPIEN vs. 60% for CoreValve (P = 0.021). In transfemorally treated patients, SAPIEN and CoreValve had similar survival at 3 years for each of the baseline EuroSCORE cohorts (low risk: 72% vs. 76%, P = 0.45; intermediate risk: 62% vs. 59%, P = 0.94; high risk: 48% vs. 53%, P = 0.65). Conclusion Cumulative midterm 3 year survival after transfemoral TAVI in real world patients refused for surgery with similar baseline EuroSCORE risk profile is not different between SAPIEN or CoreValve.
Language
English
Source (journal)
Catheterization and cardiovascular interventions. - New York, N.Y.
Publication
New York, N.Y. : 2015
ISSN
1522-1946
Volume/pages
86:3(2015), p. 528-535
ISI
000359811600038
Full text (Publisher's DOI)
Full text (open access)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 01.06.2015
Last edited 09.12.2017
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