Publication
Title
Prucalopride for constipation
Author
Abstract
Importance of the field: Chronic constipation has a high prevalence, and current medical and pharmacological therapies do not restore normal bowel function in all patients. Areas covered in the review: A PubMed search (1965 2009) using the following terms alone or in combination: prucalopride, 5-HT4, R093877, safety, toxicity, pharmacokinetics, pharmacodynamics, transit, cardiac, hERG, arrhythmia, potassium current, elderly. What the reader will gain: Understanding of the mechanisms of action, safety, efficacy and indications for prucalopride in patients with chronic constipation. Take home message: Prucalopride is an efficacious and generally safe, new therapeutic option in the management of chronic constipation.
Language
French
Source (journal)
Expert opinion on pharmacotherapy. - London
Publication
London : 2010
ISSN
1465-6566
Volume/pages
11:3(2010), p. 451-461
ISI
000276194700010
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 27.06.2015
Last edited 27.05.2017