Title
Adjuvant chemoradiation therapy in gastric cancer : critically reviewing the past and visualizing the next step forward Adjuvant chemoradiation therapy in gastric cancer : critically reviewing the past and visualizing the next step forward
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Publication type
article
Publication
New york :Hindawi publishing corporation ,
Subject
Human medicine
Source (journal)
Gastroenterology Research and Practice
Volume/pages
(2015) , 9 p.
ISSN
1687-6121
1687-6121
Article Reference
650846
Carrier
E-only publicatie
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Gastric cancer remains one of the most common malignancies worldwide. Despite the significant advances in surgical treatment and multimodality strategies, prognosis has modestly improved over the last two decades. Locoregional relapse remains one of the main issues and the combined chemoradiation treatment seems to be one of the preferred approaches. However, more than ten years after the hallmark INT-0116 trial, minimal progress has been made both in terms of effectiveness and toxicity. Moreover, new regimens added to combined therapy failed to prove favourable results. Herein, we attempt a thorough literature review comparing pros and cons of all relative studies and potential bias, targeting well-designed future approaches.
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Full text (open access)
https://repository.uantwerpen.be/docman/irua/dba194/126444.pdf
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Handle