Publication
Title
Adjuvant chemoradiation therapy in gastric cancer : critically reviewing the past and visualizing the next step forward
Author
Abstract
Gastric cancer remains one of the most common malignancies worldwide. Despite the significant advances in surgical treatment and multimodality strategies, prognosis has modestly improved over the last two decades. Locoregional relapse remains one of the main issues and the combined chemoradiation treatment seems to be one of the preferred approaches. However, more than ten years after the hallmark INT-0116 trial, minimal progress has been made both in terms of effectiveness and toxicity. Moreover, new regimens added to combined therapy failed to prove favourable results. Herein, we attempt a thorough literature review comparing pros and cons of all relative studies and potential bias, targeting well-designed future approaches.
Language
English
Source (journal)
Gastroenterology Research and Practice
Publication
New york : Hindawi publishing corporation, 2015
ISSN
1687-6121
Volume/pages
(2015), 9 p.
Article Reference
650846
ISI
000355846200001
Medium
E-only publicatie
Full text (Publishers DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 02.07.2015
Last edited 09.05.2017
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