Publication
Title
Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy
Author
Abstract
Gamma delta (γδ) T cells are the all-rounders of our immune-system with their major histocompatibility complex-unrestricted cytotoxicity, capacity to secrete immunosti-mulatory cytokines and ability to promote the generation of tumor antigen-specific CD8+ and CD4+ T cell responses. Dendritic cell (DC)-based vaccine therapy has the prospective to harness these unique features of the γδ T cells in the fight against cancer. In this review, we will discuss our current knowledge on DC-mediated γδ T cell activation and related opportunities for tumor immunologists.
Language
English
Source (journal)
Oncoimmunology
Publication
2015
ISSN
2162-4011
2162-402X
Volume/pages
4:8(2015), 9 p.
Article Reference
e1021538
ISI
000360239300013
Medium
E-only publicatie
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 30.09.2015
Last edited 18.11.2017
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