Ferritin and body mass index predict cardiac dysfunction in female adolescents with anorexia of the restrictive typeFerritin and body mass index predict cardiac dysfunction in female adolescents with anorexia of the restrictive type
Faculty of Medicine and Health Sciences
Laboratory Experimental Medicine and Pediatrics (LEMP)
Epidemiology and social medicine (ESOC)
Acta cardiologica. - Bruxelles
70(2015):4, p. 395-399
University of Antwerp
Background and aim Decreased left ventricular mass index in anorexia nervosa is amply reported. The aim of this study is to identify non-burdensome predictors of reduced left ventricular mass/height(2.7) (cLVM) in a cohort of adolescent restrictive anorexic girls. Methods This is a retrospective study of all anorexic girls of the restrictive type referred to our tertiary eating disorder unit between September 2002 and December 2012, for somatic assessment of weight loss. All subjects fulfilled DMS-IV criteria, without a family history of cardiac or cardiovascular diseases. Results In all, 283 restrictive anorexic girls (age: 14.63 +/- 1.65 y; body mass index: 15.72 +/- 1.81 kg/m(2)) were included. Ferritin and body mass index were independent, statistically significant predictors of the corrected left ventricular mass (P <0.05). Conclusion Decreased cLVM is very common in anorexia nervosa of the restrictive type.Two factors predicted decreased cLVM in our population: ferritin and BMI.